Dossier
senolytics
Coverage of senolytics in the Nexus archive.
Jamie Justiceperson1Peter Diamandisperson1XPRIZE Healthspanorganization1Wake Forest Universityorganization1longevity researchtopic1University of South Alabamaorganization1Journal of the American Heart Associationorganization1interleukin-16topic1navitoclaxtopic1high-salt diettopic1cellular senescencetopic1vascular agingtopic1
- STAT+: The woman behind the world’s biggest longevity competition
Jamie Justice, an anti-aging researcher, co-founded the $101 million XPRIZE Healthspan competition with Peter Diamandis to identify therapies restoring muscle, cognition, and immune function in older adults. The initiative selects 10 teams from 40 to conduct yearlong clinical trials, with results expected by 2030.
- Common eating habit may trigger premature immune system aging, study finds
A study from the University of South Alabama found that a high-salt diet triggers the immune system to release interleukin-16 (IL-16), causing premature aging of blood vessel cells and impairing their function. Experimental senolytic drugs like navitoclax reversed this damage in mice but face challenges in human application.