melanoma
Coverage of melanoma in the Nexus archive.
- Tanning Is Getting Hot Again. Here's What It Really Does to Your Skin.
Nichole Sims began using tanning beds at age 15, influenced by peers before events like homecoming and prom. Eight years later, she was diagnosed with melanoma. The article highlights the health risks of tanning bed use.
- Tanning is getting hot again. Here’s what it really does to your skin
Nichole Sims was diagnosed with melanoma after using tanning beds as a teenager. Experts warn that tanning bed use increases melanoma risk due to high UV exposure causing DNA mutations. Social media is fueling a resurgence in tanning popularity among young people, despite health risks highlighted by studies and organizations like the American Cancer Society.
- FDA advisory panel backed Replimune's twice-rejected melanoma treatment in 10-3 vote
The FDA advisory panel supported Replimune's melanoma treatment RP1 in a 10-3 vote, increasing its chances of approval before the Aug. 2 deadline. RP1 is an engineered viral immunotherapy previously rejected by the FDA.
- Tanning is getting hot again. Here’s what it really does to your skin
Nichole Sims, who developed melanoma after using tanning beds, warns against tanning trends fueled by social media. A study found tanning bed users have triple the melanoma risk compared to nonusers, with UV exposure from beds emitting over 10 times more radiation than sunlight. A 2025 survey shows Gen Z prioritizes tanning over sun protection and believes myths like 'base tans' prevent sunburn.
- FDA Staff Unconvinced Drug for Melanoma Shows Benefit
FDA staff remains unconvinced that the melanoma drug candidate RP1 (vusolimogene oderparepvec) demonstrates sufficient benefit. The drug, previously rejected twice by the FDA, faces potential challenges at an upcoming FDA outside experts meeting.
- 26-year-old shares dire warning — just 3 months before dying of melanoma: ‘This could have been caught earlier’
A 26-year-old shares a dire warning about melanoma, stating they now live with stage four metastatic melanoma and regret that it could have been detected earlier. They describe the daily struggle to find treatments that might save their life.
- John was devastated to learn he had melanoma that had spread to his lungs, liver and kidney. The worst part? He had just one symptom - and it WASN'T on his skin…
John was diagnosed with melanoma that had spread to his lungs, liver, and kidney. He experienced only one symptom, which was not related to his skin.
- Colorado sees increase in melanoma cases as UV exposure remains high
Melanoma cases in Colorado have increased over the past two decades, with a significant jump in 2020, according to state data. Dermatologist Maggie Catalano attributes the rise to greater awareness and preventive measures, such as regular skin checks and UV protection. Colorado's high elevation and strong UV exposure are highlighted as contributing factors to the risk.
- 8 common sunscreen mistakes upping your risk of deadly melanoma
The article highlights 8 common sunscreen mistakes that increase the risk of deadly melanoma. It warns that enjoyable sun activities can lead to serious health consequences.
- Teddi Mellencamp gives rare update on what ‘cancer recovery looks like’ in tearful video
Teddi Mellencamp shared a rare update on her cancer recovery in a tearful video. She had previously announced a Stage 2 melanoma diagnosis in October 2022.
- ‘She really was perfect’: 28-year-old softball standout dies after cancer leaves her paralyzed
Emily Bounds, a 29-year-old former softball player from Moody, Texas, died after battling stage 4 melanoma that left her paralyzed. The community raised over $100,000 through a fundraiser to help her purchase a wheelchair-accessible van. Her coach and friends described her as a resilient leader who inspired others through her fight against the disease.
- Richard Scolyer, cancer researcher and former Australian of the year, dies aged 59
Richard Scolyer, a cancer researcher and former Australian of the year, died at 59. He was diagnosed with inoperable brain cancer in 2023 and conducted pioneering work on immunotherapy. His family shared a statement he wrote before his death.
- ‘You can’t give up’: South Florida teacher shares cancer survival story ahead of Survivors Day
Mary Suppe, a South Florida teacher, shares her cancer survival story ahead of Cancer Survivors Day, detailing her battle with melanoma that spread to her brain and her recovery through treatment and a positive mindset. She participated in an early immunotherapy clinical trial and now shows no signs of cancer.
- Could cancer vaccines be next? New treatment cuts melanoma risk by nearly 50%
A new personalized mRNA cancer therapy, intismeran autogene, combined with KEYTRUDA, reduced melanoma recurrence or death risk by 49% over five years in a phase 2b study. The treatment, developed by Merck and Moderna, showed sustained benefits and a manageable safety profile in high-risk melanoma patients. It is now in phase 3 trials.
- Personalized mRNA vaccine shows promise in reducing melanoma return: Research
A personalized mRNA vaccine developed by Moderna and Merck shows promise in reducing the recurrence of melanoma, the deadliest form of skin cancer, according to a five-year follow-up of a Phase 2b study.
- A cancer vaccine made just for you. mRNA is back and it's fighting melanoma
A study found an mRNA vaccine highly effective in preventing melanoma recurrence when combined with Keytruda, an immunotherapy drug. The vaccine targets this dangerous skin cancer using personalized mRNA technology.
- A cancer vaccine made just for you. mRNA is back and it's fighting melanoma
A study found that an mRNA vaccine is highly effective at preventing recurrence of melanoma when used in combination with Keytruda, an immunotherapy drug.
- Why cancer spreads more in middle age than in old age
Researchers discovered that melanoma spread in mice is lowest in young mice, peaks in middle age, and declines again in very old mice. A specific immune cell type appears to regulate cancer dormancy and prevent metastasis, challenging previous assumptions about age-related cancer progression.
- Riskiest skin cancer cases hit UK record high
Melanoma skin cancer cases in the UK have reached a record high, surpassing 20,000 cases annually for the first time. This represents a significant increase in the most dangerous type of skin cancer diagnosis rates across the country.
- Skin cancer cases in the UK hit record highs as charity issues urgent sun safety warning
Skin cancer cases in the UK have reached record high levels, prompting a charity to issue an urgent warning about sun safety. The increasing incidence reflects growing concerns about UV exposure and melanoma rates among the British population.
- Melanoma skin cancer cases in UK hit record level, analysis finds
Melanoma cases in the UK have reached a record high of 20,980 diagnoses in 2022, marking the first time the number has exceeded 20,000. This represents a significant increase in the most serious form of skin cancer according to Cancer Research UK's analysis of the latest figures.
- Skin cancer 'set to surge by 2050' with cases of deadly melanoma and other forms rising worldwide, major study warns
A major study warns that skin cancer cases, including deadly melanoma, are expected to surge worldwide by 2050. This increase is a global concern, with rising cases of various forms of skin cancer. The study highlights the need for awareness and preventive measures.
- RFK Jr. clears path for minors' use of tanning beds, much to the dismay of dermatologists
RFK Jr. has cleared the path for minors to use tanning beds, despite a proposed FDA rule intended to protect children from indoor tanning, which increases melanoma risk by 75%. This decision has been met with dismay from dermatologists. The removal of the proposed rule may put children at greater risk.
- Bank Holiday skin cancer warning as shocking number of Britons who DELIBERATELY sunburn 'to get a tan' is revealed... increasing their risk of deadly melanoma
A shocking number of Britons deliberately sunburn themselves to achieve a tan, increasing their risk of deadly melanoma. The Bank Holiday period has prompted warnings about the health dangers of intentional sunburn.
- Scientists discover hidden “master switch” driving skin cancer growth and immune escape
Scientists identified HOXD13 as a key protein that drives melanoma tumor growth and immune evasion by enhancing blood supply and suppressing cancer-fighting T cells. Disabling HOXD13 reduces tumors and restores immune system activity, offering a potential new treatment approach for skin cancer.
- AI identifies early risk patterns for skin cancer
A Swedish study demonstrates that AI can identify individuals at higher risk of melanoma using routine health data. The AI models outperformed basic methods, accurately flagging high-risk groups with some individuals having a 33% chance of developing melanoma within five years. This could lead to more targeted and effective skin cancer screening.
- Mapping convergent regulators of melanoma drug resistance by PerturbFate
PerturbFate, a high-throughput single-cell platform, identifies common regulatory nodes and phenotypic states linked to vemurafenib resistance in melanoma cells. The study, published in Nature, uses CRISPR interference to map convergent regulators of drug resistance in melanoma.