Dossier
lysosomes
Coverage of lysosomes in the Nexus archive.
- LASER couples damage sensing to ESCRT assembly for lysosome repair
ATG8 conjugation on damaged lysosomes triggers rapid assembly of a protein complex containing TFG, which recruits ESCRT proteins to repair lysosomal membranes. This process links damage sensing to ESCRT-mediated lysosome repair.
- Scientists make old blood stem cells young again in major anti-aging breakthrough
Scientists have made a breakthrough in anti-aging by restoring the youthful function of old blood stem cells. The researchers achieved this by calming the cellular overdrive that occurs as blood stem cells age. This restoration dramatically boosts the ability to regenerate and produce balanced blood cells.