Dossier
ATG8 conjugation
Coverage of ATG8 conjugation in the Nexus archive.
- LASER couples damage sensing to ESCRT assembly for lysosome repair
ATG8 conjugation on damaged lysosomes triggers rapid assembly of a protein complex containing TFG, which recruits ESCRT proteins to repair lysosomal membranes. This process links damage sensing to ESCRT-mediated lysosome repair.