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genome-wide association study

Coverage of genome-wide association study in the Nexus archive.

Earliest in view: Jun 3 · 00:00 UTCMost recent: Jun 3 · 00:00 UTC
Co-mentioned in this coverage
Natureorganization1inflammatory bowel diseasetopic1cell-type-resolved genetic variationtopic1cis-expression quantitative trait locitopic1
Recent coverage
  • HEALTHJun 3 · 00:00 UTCNATURE NEWS
    Cell-type-resolved genetic variation shapes inflammatory bowel disease risk

    A study published in Nature reveals that cell-type-specific genetic variants in inflammatory bowel disease (IBD) co-localize more frequently with genome-wide association study (GWAS) loci when analyzed at the cell-type level compared to the tissue level. Single-cell mapping of cis-expression quantitative trait loci (cis-eQTLs) identified distal, enhancer-enriched variants linked to IBD risk.