Dossier
VSG diversification
Coverage of VSG diversification in the Nexus archive.
- DNA damage drives antigen diversification in Trypanosoma brucei
A study published in Nature reveals that DNA damage drives antigen diversification in Trypanosoma brucei, enabling the parasite to evade immune responses. Researchers developed an in vitro toolkit to understand molecular mechanisms behind mosaic VSG formation, offering insights into antigen diversification strategies in pathogens.