Sickle Cell Disease
Coverage of Sickle Cell Disease in the Nexus archive.
- FDA approves gene therapy for children with sickle cell disease ages 2+
The FDA approved gene therapy for treating sickle cell disease in children aged 2 and older. A Nashville doctor described the approval as a medical milestone.
- Gene therapy for children with sickle cell disease approved by FDA
The FDA has approved a new gene therapy treatment for children aged 2 or older with sickle cell disease. This marks a significant advancement in managing the condition.
- Bucknell coach charged with hazing in freshman football recruit’s 2024 death
A Bucknell University football strength coach, Mark Kulbis, is charged with felony aggravated hazing and involuntary manslaughter after a freshman recruit, Calvin Dickey Jr., died in 2024 from stress-induced sickle cell disease following a punitive workout. The Pennsylvania Attorney General’s Office alleges Kulbis disregarded training on handling athletes with sickle cell trait and ignored warnings about Dickey’s condition, leading to his death.
- South Florida teen urgently needs rare, lifesaving blood match as she battles painful disease
An 18-year-old South Florida teen with sickle cell disease urgently needs 50 units of rare O-negative blood from African American donors to proceed with a lifesaving bone marrow transplant. Her brother is a perfect marrow match, but multiple prior transfusions have made finding compatible blood challenging, requiring urgent donations.
- ‘A leap of faith’: Nashville teen makes history with gene-editing treatment for sickle cell disease
A 13-year-old Nashville boy, Rickey Buggs, underwent a 42-day gene-editing treatment at TriStar Centennial Children’s Hospital under Dr. Haydar Frangoul, potentially offering a cure for his sickle cell disease. The therapy, described as transformative, marks a significant advancement for patients without family matches for traditional treatments.
- STAT+: A year after distressed buyout, what’s become of Bluebird Bio?
David Meek acquired Bluebird Bio (now rebranded as Genetix) when it was near bankruptcy and claims to have transformed it in a year. He predicts the company will treat 1,000 patients annually for sickle cell disease gene therapies by 2030.
- Groundbreaking research led in Nashville could change sickle cell treatment for children
Groundbreaking research led by a Nashville physician could change treatment for children with sickle cell disease and another inherited blood disorder. The study offers hope for improved outcomes in these conditions.
- Louisiana man becomes first in state functionally cured of sickle cell disease
Daniel Cressy, a 23-year-old Louisiana man, became the first person in his state to be functionally cured of sickle cell disease through gene therapy at Manning Family Children’s Hospital in New Orleans. The treatment enables him to pursue his career as a commercial pilot, and Louisiana has the highest rate of sickle cell disease cases in the US.
- 23-year-old becomes first in state functionally cured of sickle cell disease
A 23-year-old New Orleans man became the first in Louisiana to be functionally cured of sickle cell disease through gene therapy. Daniel Cressy underwent the treatment at Manning Family Children’s Hospital and now plans to establish a nonprofit to support others with the disease.
- 23-year-old becomes first in state functionally cured of sickle cell disease
A 23-year-old New Orleans man, Daniel Cressy, became the first person in Louisiana to be functionally cured of sickle cell disease through gene therapy. The procedure, conducted at Manning Family Children’s Hospital, involved editing his stem cells to eliminate the defective cells causing the disease, with Cressy now planning to support others through his nonprofit.
- 23-year-old becomes first in state functionally cured of sickle cell disease
Daniel Cressy, a 23-year-old from Louisiana, is the first in the state to be functionally cured of sickle cell disease via gene therapy at Manning Family Children’s Hospital. The procedure used his own edited stem cells, and he aims to launch a nonprofit to support others undergoing similar treatment.
- PT HEALTH WATCH: Sickle cell disease persists in Nigeria despite decades of awareness
Sickle cell disease remains a persistent issue in Nigeria despite decades of awareness, with experts citing inadequate newborn screening, poor treatment access, weak primary healthcare, and misconceptions about the disease. Medical and maternal health professionals highlighted these systemic gaps during discussions on World Sickle Cell Day.
- Brave NYC boy with sickle cell disease gets heartwarming ‘VIP’ treatment at Knicks game
A brave Manhattan boy with sickle cell disease received VIP treatment at a Knicks game, organized by a charity that partners with Madison Square Garden, allowing him to enjoy the event despite his condition.
- STAT+: Patients jockey for exemptions from Medicaid’s new work requirements
Patient groups are seeking exemptions from new Medicaid work requirements, which will be implemented by January 1. Federal officials have until June 1 to provide guidance to states. Advocates for patients with certain diseases, such as sickle cell disease and HIV, are meeting with federal officials to request exemptions.
- Man produces sperm from testicular tissue frozen as a child in breakthrough trial
A 27-year-old man has produced sperm from testicular tissue frozen as a child in a breakthrough trial, offering hope to boys left infertile by chemotherapy. The tissue was frozen when he was 10 and re-transplanted 16 years later. This is the first time a transplant of cryopreserved prepubertal testicular tissue has restored sperm production in an adult patient.