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NFIL3

Coverage of NFIL3 in the Nexus archive.

Earliest in view: Jun 2 · 14:54 UTCMost recent: Jun 2 · 14:54 UTC
Co-mentioned in this coverage
CAR T-cell therapytopic1immune cellstopic1cancer-fighting powertopic1animal modelstopic1
Recent coverage
  • HEALTHJun 2 · 14:54 UTCSCIENCE DAILY
    A single protein may be holding back CAR T cancer therapy

    A newly identified protein called NFIL3 is found to cause CAR T-cell therapy to lose effectiveness over time by inducing exhaustion in engineered immune cells. Disabling NFIL3 in animal models improved the cells' strength and tumor control.

NFIL3 · Dossier · The Nexus