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GLP-1R

Coverage of GLP-1R in the Nexus archive.

Earliest in view: Apr 29 · 00:00 UTCMost recent: Apr 29 · 00:00 UTC
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  • HEALTHApr 29 · 00:00 UTCNATURE NEWS
    GLP-1R–GIPR–PPARα/γ/δ quintuple agonism corrects obesity and diabetes in mice

    A single-molecule agonist targeting GLP-1R, GIPR, and PPARα/γ/δ receptors (GLP-1–GIP–lanifibranor) demonstrates therapeutic efficacy in correcting obesity and diabetes in mouse models through synergistic metabolic pathways. Published in Nature, the study highlights its potential for treating obesity-linked metabolic dysfunction.

GLP-1R · Dossier · The Nexus