Dossier
CRISPR interference
Coverage of CRISPR interference in the Nexus archive.
- Mapping convergent regulators of melanoma drug resistance by PerturbFate
PerturbFate, a high-throughput single-cell platform, identifies common regulatory nodes and phenotypic states linked to vemurafenib resistance in melanoma cells. The study, published in Nature, uses CRISPR interference to map convergent regulators of drug resistance in melanoma.