CRISPR

Gene-editing startups are utilizing CRISPR technology to develop therapies targeting specific epigenetic markers. These treatments aim to address conditions such as high cholesterol and a rare muscular disorder.

Feng Zhang, a CRISPR expert, argues that immigration should be viewed as an economic and national security asset for science.

CRISPR, short for Clustered Regularly Interspaced Short Palindromic Repeats, is an immune system evolved in bacteria to defend against viral threats. It functions by snipping and storing fragments of viral DNA in the CRISPR region for future defense.

A US-based team has achieved promising results using an improved CRISPR method to gene-edit human embryos. However, a significant issue remains unresolved, raising ongoing concerns about safety and ethical implications.

Scientists have precisely edited human embryo genes for the first time, a development that has sparked serious debate for over a decade following the invention of CRISPR.

Season Five of 'The Joy of Why' explores bold scientific questions, including the future of CRISPR gene editing, AI's impact on mathematics, the search for extraterrestrial civilizations, and potential misunderstandings about dark energy. Mathematician Steven Strogatz and physicist Janna Levin return as hosts.

The anti-CRISPR protein AcrVA2 disrupts Cas12a biogenesis by inducing co-translational degradation of cas12 mRNA. This mechanism highlights a novel regulatory pathway in CRISPR systems.

Researchers are using CRISPR technology to target the extra chromosome associated with Down syndrome, marking a significant advancement in genetic therapy. This breakthrough could potentially lead to new treatments for the condition.