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The Nexus
HEALTHApr 1 · 00:00 UTCNATURE NEWSDavid H. Rowitch

DNA damage burden causes selective CUX2 neuron loss in neuroinflammation

A study published in Nature reveals that DNA damage burden and inadequate repair in CUX2+ cortical layer 2/3 excitatory neurons contribute to selective vulnerability in neuroinflammatory injury. The research highlights the role of DNA damage mechanisms in neuron loss during neuroinflammation, offering potential insights for therapeutic interventions.

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DNA damage burden causes selective CUX2 neuron loss in neuroinflammation · The Nexus