Dossier
therapy target
Coverage of therapy target in the Nexus archive.
- This missing vitamin could stop cancer cells in their tracks
Cancer cells rely on glutamine but can switch fuels using vitamin B7 (biotin), which acts as a metabolic 'license' via a key enzyme. Without biotin, cancer cells lose this metabolic flexibility and stop growing. Mutations in a cancer-linked gene amplify this vulnerability, offering a potential new therapeutic target.