Dossier
single-cell four-omics sequencing
Coverage of single-cell four-omics sequencing in the Nexus archive.
- Gene regulatory landscape dissected by single-cell four-omics sequencing
A study published in Nature on April 1, 2026, employs single-cell four-omics sequencing to analyze genome conformation, histone modifications, chromatin accessibility, and gene expression. This approach reveals dynamic epigenome profiles and spatial clustering within cells, advancing understanding of regulatory landscapes across tissues.