Dossier
ribosomes
Coverage of ribosomes in the Nexus archive.
- Protein traffic jams may explain aging, memory loss, and Alzheimer’s
Scientists at Stanford discovered that ribosomes, the cellular machinery for building proteins, begin to jam and malfunction over time in turquoise killifish. This leads to faulty proteins and harmful clumps linked to Alzheimer’s and aging-related cognitive decline.
- STAT+: How a global effort to explore the ‘dark proteome’ is upending our understanding of human disease
Sebastiaan van Heesch used a new method to analyze ribosomes in donated hearts and discovered hundreds of previously unknown mini-proteins. These 'dark proteins' may influence energy production in heart muscles. The findings could change our understanding of human disease.