rapamycin
Coverage of rapamycin in the Nexus archive.
- A single dose reversed autism-like symptoms in adult mice within hours
Mild pregnancy inflammation caused brain overactivity, sensory sensitivity, repetitive behaviors, and increased seizure risk in mouse offspring. A single dose of rapamycin reversed nearly all these autism-like symptoms within two hours, though benefits were temporary, suggesting adult brain circuits may be more adaptable than previously believed.
- One dog's impact on the science of aging
The Rowe family's dog Ralph, who had dementia, participated in a study on rapamycin. Scientists gained new insights into the drug's potential as a treatment by analyzing his brain.
- Ralph the dog's impact on science and his family
Ralph, the Rowe family dog, participated in a study of rapamycin with other canines with dementia. Scientists gained new insights into the drug's potential as a treatment by analyzing his brain.