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next-generation echinocandins

Coverage of next-generation echinocandins in the Nexus archive.

Earliest in view: Apr 22 · 00:00 UTCMost recent: Apr 22 · 00:00 UTC
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  • SCIENCEApr 22 · 00:00 UTCNATURE NEWS
    Structural basis of fungal β-1,3-glucan synthase inhibition by caspofungin

    A study published in Nature reveals the structural basis of how caspofungin inhibits fungal β-1,3-d-glucan synthase. This discovery could enable the development of next-generation echinocandins with enhanced potency, broader antifungal activity, and reduced resistance risks.