Dossier
glycerol
Coverage of glycerol in the Nexus archive.
- Scientists discover hidden fat-burning switch that could strengthen bones
Scientists at McGill University discovered a hidden molecular switch that activates a powerful calorie-burning system in brown fat, which could strengthen bones and aid in weight control. The breakthrough involves glycerol, a molecule released when fat is broken down in cold temperatures. This discovery may lead to new treatments for related health issues.
- Glycerol-driven TNAP activation in thermogenesis and mineralization
Glycerol acts as an allosteric activator for tissue-nonspecific alkaline phosphatase (TNAP), linking it to thermogenesis and mineralization processes. This activation drives the futile creatine cycle, a metabolic mechanism with potential implications in energy regulation.