biomarkers
Coverage of biomarkers in the Nexus archive.
- Objective metrics that change the most as we age
The article from Empirical Health's blog discusses biomarkers that undergo the most significant changes with age, highlighting objective metrics linked to aging. It is associated with a Hacker News thread but has no comments.
- Diet change tied to ‘younger’ biological age in older adults after 4 weeks
A University of Sydney study found that changing diets in older adults (aged 65-75) for four weeks reduced their biological age in three of four diet groups. Diets varied in protein sources (animal vs. plant-based) and macronutrient focus (high-fat vs. high-carb), with the most significant improvements seen in diets rich in complex carbohydrates and plant-based components. Researchers caution results are preliminary and may reflect short-term effects.
- Delivering an immune therapy into tumours instead of intravenously reduces adverse effects
A study found that injecting low doses of anticancer immunotherapy directly into tumors in advanced skin cancer patients reduced severe immune toxicity compared to high-dose intravenous administration, while maintaining antitumor efficacy. Pre-existing antitumor immunity was the strongest predictor of clinical benefit, and fresh tissue profiling provided faster biomarker results than conventional diagnostics.
- How aggressive breast cancer turns off the immune system
Researchers are launching a new project to study how aggressive breast cancer suppresses the immune system, aiming to identify biomarkers for more precise treatments. The initiative uses real patient samples to develop clinical tools that could revolutionize personalized cancer care.
- Scientists discover hidden gut signals that could detect cancer early
Scientists have discovered that gut bacteria and metabolites can be used to detect serious digestive diseases earlier using AI, potentially leading to faster diagnoses without invasive procedures.