Zola

Kevin Ryan’s AlleyCorp has raised a $335 million second fund focused on early-stage investments in healthcare, deep tech, and general tech. The firm, previously a family office, now has eight unicorns in its portfolio and has backed psychedelic research initiatives and companies like Transcend Therapeutics, which was sold for $1.2 billion.

GLP-1 weight-loss drugs are causing significant body transformations in brides, prompting bridal retailers to adjust inventory, expedite orders, and issue fit guarantees. Shops now require waivers for dresses that may not yet fit due to ongoing weight loss, with David’s Bridal introducing a 'Fit Guarantee' to address size-related anxieties. Surveys indicate rising GLP-1 usage among couples planning weddings.

Venture capitalist Nisha Dua highlights the increasing difficulty for emerging managers to raise funds as capital consolidates around established firms. She advises focusing on a clear thesis and positioning, citing BBG Ventures' success with diverse founders and early investments in companies like Spring Health and Starface.