Dossier
HIV-1
Coverage of HIV-1 in the Nexus archive.
- HIV-1 signalling remodels nuclear pores to licence infection
HIV-1 signalling remodels nuclear pores to licence infection by triggering receptor-mediated signalling during cell-cell spread. This process overcomes the bottleneck of HIV-1 capsid nuclear import at the nuclear pore complex, allowing for resting T cell infection. The study was published in Nature on May 6, 2026.