Dossier
CASP competition
Coverage of CASP competition in the Nexus archive.
- STAT+: Drug metabolism AI competition results show that bigger may not always be better
A drug metabolism AI competition highlights that larger AI models may not always be superior, focusing on solving drug development challenges like predicting activation of the pregnane X receptor (PXR), which regulates an enzyme breaking down 50% of marketed drugs. Reliable AI prediction of PXR activation could address issues like rapid drug elimination and drug–drug interactions.