AstraZeneca
Coverage of AstraZeneca in the Nexus archive.
- STAT+: AstraZeneca to pay $34 million to settle kickback charges filed by Texas attorney general
AstraZeneca agreed to pay $34 million to settle claims that the company paid kickbacks through a free network of nurses and insurance support services to boost prescriptions in Texas Medicaid. The state alleged these actions led to unauthorized reimbursements under the Texas Health Care Program Fraud Prevention Act.
- STAT+: Moderna co-founder Kenneth Chien on the future of mRNA — and Moderna
Kenneth Chien, a co-founder of Moderna, received an Hermes belt from CEO Stéphane Bancel after securing a partnership with AstraZeneca. This deal accelerated Moderna's growth, leading to significant funding and the development of mRNA-based Covid vaccines, though the planned drugs for cancer and cardiovascular disease did not materialize.
- Weight loss without muscle loss? The next generation of drugs is testing the idea
Pharmaceutical companies are developing drugs to preserve muscle mass during weight loss, addressing an issue with existing GLP-1 drugs like Ozempic. Candidates such as bimagrumab, SPX-001, and CagriSema aim to reduce fat while retaining lean mass, with Cambrian Biotech testing a drug that mimics exercise to boost metabolism.
- Public scrutiny of secret Covid vaccine negotiations gets shot in the arm from EU adviser
An EU court adviser recommended rejecting the European Commission's appeals to keep vaccine contract details secret, supporting transparency campaigners' push for public access to negotiations and conflict-of-interest information. The decision upholds a lower court ruling that found the Commission failed to justify withholding key documents.
- STAT+: AstraZeneca’s GLP-1 pill shows promise in obesity, diabetes trials
AstraZeneca's investigational GLP-1 pill, elecoglipron, demonstrated significant weight loss in a Phase 2 obesity trial (11.2% after 36 weeks) and improved blood sugar control in a diabetes trial (1.74 percentage-point A1C reduction). Results were compared to oral Ozempic, which showed a smaller A1C decrease in the same study.
- AstraZeneca chief warns group could withhold new drugs in Europe
AstraZeneca chief Pascal Soriot warns that the company may withhold new drugs in Europe unless countries increase spending on innovative medicines following a US trade deal.
- AstraZeneca CEO says AI is reshaping drug development — and helping boost the odds of success
AstraZeneca CEO Pascal Soriot stated that AI is accelerating drug development and improving decision-making in research. He highlighted AI's role in increasing the likelihood of success for medicine development.
- AstraZeneca CFO Dr. Aradhana Sarin breaks down revenue growth goals
Dr. Aradhana Sarin, CFO of AstraZeneca, outlines the company's revenue growth goals.
- AstraZeneca CEO Pascal Soriot delivers remarks as firm celebrates transfer to NYSE
AstraZeneca CEO Pascal Soriot delivered remarks as the company celebrated its transfer to the NYSE. The event marks a significant milestone for the firm's stock market presence.
- STAT+: Trump’s drug-pricing deals set to be tested by new product launches
President Trump's most-favored-nation drug pricing deals with 17 drugmakers will be tested by three new prescription drugs set to launch soon. The drugs, Baxfendy (hypertension), Awiqli (insulin), and Veppanu (cancer), will offer the first public insight into the practical impacts of these secretive pricing agreements.
- STAT+: Kailera’s own ‘triple-G’ drug also looks very powerful
The FDA delayed a decision on AstraZeneca's breast cancer drug camizestrant due to advisory concerns over its trial design. Blackstone Life Sciences is investing $1.3 billion in Apogee Therapeutics for Phase 3 development of zumilokibart, a long-acting atopic dermatitis treatment. Kailera's experimental obesity drug, targeting three hormones, showed significant weight loss in a Phase 1 study.
- STAT+: Pharmalittle: We’re reading about an AstraZeneca breast cancer pill, an ADAP deal in Florida, and more
The FDA has extended the decision deadline for AstraZeneca's experimental breast cancer pill, camizestrant, to review additional data after an advisory panel raised concerns about a late-stage trial's design. Brazil approved the first generic version of Novo Nordisk's Ozempic (now Ozivy) by EMS, a pharmaceutical company, which plans to sell it at 30% lower cost.
- STAT+: EU and US advisers split over AstraZeneca breast cancer drug
EU and US regulatory advisers have diverged in their assessment of AstraZeneca's breast cancer drug, signaling potential approval challenges. The disagreement highlights different regulatory approaches between the two regions on this oncology treatment.
- STAT+: Pharmalittle: We’re reading about a Supreme Court setback for pharma, TrumpRx expands and much more
The US Supreme Court declined to hear lawsuits from brand-name pharmaceutical companies against the Medicare drug price negotiation program, and the TrumpRx prescription drug discount platform is expanding with over 600 generic drugs. The expansion is a result of partnerships with Mark Cuban's Cost Plus Drug Company, Amazon Pharmacy, and GoodRx. This development may make remaining legal challenges more difficult for the drug industry.
- STAT+: AstraZeneca picks up FDA approval for hypertension drug
AstraZeneca has received FDA approval for a hypertension drug, and the biotech industry is debating the role of China in global drug development. The FDA has also undergone leadership changes with new acting directors. AstraZeneca's approval is a significant development in the treatment of hypertension.
- STAT+: Supreme Court rejects challenge to Medicare drug price negotiation
The Supreme Court rejected a challenge to the Medicare drug price negotiation program, declining to take up lawsuits from several pharmaceutical companies. The decision is a blow to the brand drug industry's legal campaign against the program. The court did not provide a reason for its decision.
- 2026 Another Catalyst Rich Year: AstraZeneca CFO
AstraZeneca's CFO predicts 2026 will be a catalyst-rich year, signaling major events for the company.
- AstraZeneca makes surprise U-turn with £300m pharma investment
AstraZeneca has reversed its decision to pause large-scale UK projects, pledging a £300m investment in the country after previously citing dissatisfaction with the NHS and drug pricing. The announcement, made by Keir Starmer, marks a surprise shift in the company's stance on the UK business environment.
- FTSE 100 Futures, Pound Fall as Lloyds and Astra Report Earnings
FTSE 100 Futures and the British pound declined following earnings reports from Lloyds Banking Group and AstraZeneca. The market reaction suggests investor concerns over the companies' performance impacting broader economic indicators.
- Japan risks losing out without drug pricing reform, warns AstraZeneca CEO
AstraZeneca's CEO warns that Japan risks falling behind without drug pricing reform. The warning highlights potential consequences for Japan's pharmaceutical market and competitiveness.