Dossier
APOE4 gene
Coverage of APOE4 gene in the Nexus archive.
- USC scientists discover a hidden Alzheimer’s trigger and a possible way to shut it down
USC researchers have identified new drug compounds that target cPLA2, an enzyme linked to brain inflammation in Alzheimer’s disease, particularly in individuals with the APOE4 gene. The compounds aim to reduce harmful inflammation while preserving normal brain activity.