'Longevity gene' may protect the brain from Alzheimer's by boosting DNA repair, study finds

A new study found that the APOE2 variant of the APOE gene may help protect the brain from Alzheimer's disease by improving DNA repair and resisting cellular senescence. The study suggests that future treatments could aim to simulate the protective effects of APOE2 or boost DNA repair systems in the brain. This discovery could lead to new directions for therapy development, particularly for people who carry the higher-risk APOE4 variant.